Alternative treatment for a chronic disease of small ruminants, Caseous lymphadenitis (CL)

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Abstract Summary

Caseous lymphadenitis (CL), a disease caused by the bacterium Corynebacterium pseudotuberculosis, causes dry abscesses of the lymph nodes and internal organs of small ruminants. C. pseudotuberculosis is a facultative intracellular parasite, meaning it can live and reproduce inside and outside of host cells making it difficult to eliminate from both ruminants and their environment (Oreiby, 2014). New England’s sheep industry was worth approximately $10.2 million during 2017. In 2014, 43% of Maine sheep farms tested positive for CL, with estimated production losses of approximately 20% (Lichtenwalner, 2013). Common treatment practices include draining and cleaning of external abscesses, treatment with antibiotics, surgical removal of abscesses, culling, or injection of formalin into lesions (Washburn et al, 2009). However, these methods are temporary, and few antimicrobials are suitable for food animal use due to new regulations by the Food and Drug Administration (Veterinary Feed Directive, U.S. Food and Drug Administration, 2017). 

This project tested the effects of alternative, non-antibiotic treatment against C. pseudotuberculosis. Rosemary essential oil (EO) was used in vitroagainst C. pseudotuberculosisin a standard plate assay. It was found that rosemary EO prevented the growth of C. pseudotuberculosis in BHI broth and blood agar. The goal of this project was to provide preliminary data for further investigation of alternative methods to eradicate C. pseudotuberculosisboth from the farm environment and in vivo.

 

Abstract ID :
UMSS19225
Submission Type
Poster
Abstract Topic
Natural Sciences
Submission# :
345
Judge Time Slot :
PM1 (1:00 -2:00)